Bezisterim – the Best Long COVID Drug Trial Yet? BioVie Aims for a Big, Phase III Trial
Bezisterim produces moderate and broad treatment effects in several different long COVID subsets. BioVie, the drug manufacturer, hopes to move forward with a big phase III trial.
IVO-21 – A Paradigm Changer AND a Mitochondrial Drug for ME/CFS?
Could a new mitochondrial drug called IVO-21 be the answer to the energy problems in ME/CFS, fibromyalgia, and long COVID?
WASF3: A Critically Important Process in ME/CFS? Paul Hwang’s Surprising Saga
A mitochondrial disrupter called WASF3 could be dysregulating many systems in ME/CFS.
Jarred Younger on Neuroinflammation, “the” Brain Hub, the “Most Disappointing Event” and more in ME/CFS
Jarred Younger, found of the Neuroinflammation, Fatigue, and Pain lab talked about what's exciting him in ME/CFS, FM, and long COVID
Is a WEAKENED Fight/Flight System Causing ME/CFS and Long COVID? Part II
A new study suggests that a weakened fight/flight response originating in the brain may play a key role in ME/CFS and long COVID.
Frayed Brain Connections in ME/CFS Tell a Tale
Frayed brain connections help explain the cognitive, sensory, and movement problems in ME/CFS.
The Fatigue in ME/CFS Comes From the Brain … Or does it?
An NIH paper proposed that the fatigue in ME/CFS is caused by the brain. That might not be the end of the story, however.
Long COVID Study Finds Major Energy Deficits in the Brain
A long COVID study examining, for the first time, energy levels in the brain, found them to be depleted in a large region called the cingulate cortex.
The Big Long COVID Neuroplasticity Trial: Did it Work?
A large neuroplasticity long COVID trial appears to noticeably improve a small subset of patients, and has small to modest effects on most others.









