A Non-Cannabis “Cannabis” Product
The terpenes in cannabis produce its pungent odor. They are produced by the trichomes or hairs that populate its leaves. Stronger smells are often associated with greater effectiveness.
Health Rising usually doesn’t review products, but this line of products hit a sweet spot for four reasons. It was produced by Lee Know, a naturopath who was way ahead of his time when back in 2018 he wrote “Mitochondria and the Future of Medicine: The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself”. I used it as a backbone for Health Rising’s treating mitochondria series.
Know has produced a series of non-cannabis terpene products that don’t include THC or CBD, don’t appear to induce tolerance – a problem I’m running into with the cannabis product I use to help with sleep, and whose effectiveness can quickly and affordably be assessed.
If anyone remembers our 2019 “Marijuana as Medicine” series, which went into in great detail about the various properties of cannabis, the medical benefits from cannabis don’t reside only in the delta-9-tetrahydrocannabinol or THC (the great pain reliever) and cannabidiol (CBD – the stress reducer and anti-inflammatory) components in the plant.
- Marijuana as Medicine for ME/CFS and/or Fibromyalgia Pt I: The Science Behind Cannabis
- Marijuana as Medicine for ME/CFS and/or Fibromyalgia Pt II: Getting Started with Cannabis
- Marijuana as Medicine for ME/CFS and FM III: Cannabis – More Than Just THC and CBD
- Marijuana as Medicine for ME/CFS and FM IV: The Doctor Speaks – Treatment #I
- Pt V: CBD Oil – A Primer for ME/CFS and Fibromyalgia
The plant is much richer than that, and over time, other medicinal factors are coming to the fore. From pinene (improves focus, counteracts THC), to linalool (calming, sleep aid), to beta-myrcene (calming, sedative effect, muscle relaxant) to terpenes (muscle relaxant, sedative, anti-inflammatory and antibiotic) and others, many parts of the cannabis plant appear to have medicinal values.
Boosting the Endocannabinoid System – and ME/CFS/FM and Long COVID?
THC and CBD impact something called the endocannabinoid system – which is our internal cannabinoid system. It turns out that humans produce their own cannabinoid products, and the endocannabinoid system they affect is wide-reaching indeed.
If Know is right about the endocannabinoid system, then boosting it might be a good idea for people with ME/CFS, FM, long COVID, and similar diseases which feature nervous system activation. The endocannabinoid system is often portrayed as a kind of master regulator – when things go out of balance, it jumps in to return them to homeostasis. When the nervous system is too active, for instance – and my experience is that it is way too active in ME/CFS/FM – Know stated that the endocannabinoid system sends a signal back down the chain telling it to calm down.
“When it sees that there’s too much nervous system signals going down the nervous system chain, it sends a signal retroactively through a retrograde signaling. It goes from the postsynaptic neuron to the presynaptic neuron to tone down that signaling and tame that overactive nervous system. Whether it’s nerve signals or things related to inflammation.”
The status of the endocannabinoid system in diseases like ME/CFS, fibromyalgia and long COVID is, however, unclear. One review of the endocannabinoid picture in fibromyalgia concluded, though, there was “evidence for alterations in the endocannabinoid system in patients with FM”.
Two Receptors
Two receptors – CB1 and CB2 – turn the endocannabinoid system in the human body on or off. The CB1 receptors that are activated by THC – the ingredient in cannabis that provides the high – are mainly found in the brain and the central nervous system. The CB2 receptors, on the other hand, that are activated by cannabidiol (CBD and other plant factors) are mostly found in the body and do not produce a high.
(Lee’s statement – repeated several times – that products that stimulate the CB2 receptors produce “all the health benefits, but none of the high” of products that stimulate the CB1 receptors – is obviously not accurate as the two receptors work in different parts of the body. THC and the CB1 receptors they activate through are much better at relieving pain and perhaps sleep. The CB2 receptors are, however, found in just about every organ and cell in the body and thus can potentially affect inflammation more thoroughly.)
Cannanda’s Terpene Approach
The terpenes found in CBD oil.
Thousands of different terpenes provide the aromas we associate with different plants. (I well remember decades ago the difference between the Mexican weed (which smelled like grass) and the much, much, (much) more potent northern California weed with its pungent aroma.)
Cannanda has chosen to build its products around a specific kind of terpene, which – to get around legal issues regarding selling cannabis-derived products – is derived from botanical oils (not cannabis plants). (It’s still the same terpene).
The terpenes most often found in cannabis include limonene, pinene, myrcene, linalool, eucalyptol, beta-caryophyllene, and some others. Studies indicate that beta-caryophyllene, humulene, and pinene have anti-inflammatory effects.
Cannanda, and other companies like Copaiba, focus on beta-caryophyllene because it’s the only terpene that binds to the CB2 receptor and thus directly activates the endocannabinoid system. Because it binds more effectively to the CB2 than CBD, it’s probably a more potent activator of that system. Plus, beta-caryophyllene also activates the μ-Opioid receptor, potentially enhancing its effectiveness with pain.
While Know reports that because terpenes are essential oils that evaporate quickly, our food distribution system – which often requires shipping fruits and vegetables vast distances – can leave our food less terpene-rich.
While human studies appear to be lacking, animal and laboratory studies suggest beta-caryophyllene may be able to reduce inflammation in the brain and function as an antioxidant, reduce anxiety, relieve pain, and even improve bone density.
Another review suggested that beta-carophyllene may be able to improve mitochondrial functioning. A black pepper extract called Viphyllin™ containing 30% β-caryophyllene reduced anxiety-like behavior, brain antioxidant status, intestinal inflammation, and intestinal barrier function in an animal model.
An extensive review stated that “beta-caryophyllene may be highly effective in the treatment of long-lasting, debilitating pain states” in part because it triggers β-endorphin release which, in turn, activates the body’s opioid pain-reducing system. The article concluded:
“The data accumulated so far both in in vivo and in vitro studies show that BCP (beta-caryophyllene) is a good candidate in the treatment of chronic inflammation due to its specific molecular targets and very low toxicity.”
Know stated that the three main health conditions that people used his products for were pain, sleep issues, and anxiety. He also noted that he’s seen some incredible stories from migraine to Alzheimer’s patients. It seems that when the right biology meets the right product or approach, things can really pop.
Cannanda reports that its products “often work within the first week or two—with many users reporting it works from the very first use, almost instantly!” – meaning that one bottle will tell the tale.
Beta-caryophyllene Combination Treatments
THE GIST
- Beta-caryophyllenes are chemicals found in cannabis and other plants (such as black pepper) that are able to activate the endocannabinoid system in humans.
- The endocannabinoid system in humans is tasked with returning our systems to balance, or homeostasis. Among the things it purportedly can do is to calm an overactive nervous system and reduce inflammation – not a bad thing to do in people with diseases like ME/CFS, fibromyalgia, and long COVID.
- While better-known chemicals in cannabis such as cannabidiol (CBD) activate the endocannabinoid system, beta-caryophyllene is actually more effective at activating a branch of the endocannabinoid system that helps with inflammation, mood, and sleep.
- A review article concluded that, “The data accumulated so far both in in vivo and in vitro studies show that BCP (beta-caryophyllene) is a good candidate in the treatment of chronic inflammation due to its specific molecular targets and very low toxicity.”
- The Cannanda products featured in this blog are enticing because Cannanda reports that its “often work within the first week or two—with many users reporting it works from the very first use, almost instantly!” – meaning that one bottle will tell the tale (!).
- Note, though, that some studies have found that beta-caryophyllene may work better when combined with cannabidiol (CBD) or other factors such as pregnenolone (see end of blog).
- Health Rising is not affiliated with nor receives any money from the selling of Cannanda products!
The trial included beta-caryophyllene (40 mg) (inflammation and pain), pregnenolone (40 mg) (inflammation), St. John’s Wort (150 mg) (autonomic dysfunction), Boswellia serrata gum (100 mg) (inflammation), DHEA (30 mg) (HPA axis/anti-inflammatory), bromelain (416 mg) (anti-inflammatory/antiviral), quercetin (40 mg) (anti-inflammatory/immune modulator/antioxidant), zinc compound (12 mg) (preserve tissue barriers, immune functioning), vitamin D (25 ug). All nutraceuticals were taken twice a day with food. (Note that people taking serotonin-related antidepressants should not take St. John’s Wort extract.)
The study found that 88% of the participants benefited from the treatment, with most participants stating that most of their symptoms were improved, and 59% of the participants reported an overall improvement of their wellbeing.
Conclusion
Could beta-caryophyllene help with pain, anxiety, or sleep in ME/CFS, FM, or long COVID? I don’t know. I’ve never tried Cannanda’s products (or other brands that focus on beta-caryophyllene) but its approach using a factor found in cannabis which does not produce a high – and does not appear to produce tolerance – is intriguing.
Like the green light products that Health Rising reviewed recently, these products hit a nice sweet spot – they are readily available, are affordable, and can quickly be tested out. They might be worth a try! (Note that beta-caryophyllene might be more effective when taken with CBD, pregnenolone, or other products). If you’ve tried them, please tell us how it went.
Please note that Health Rising is not affiliated in any matter with Lee Know or Cannanda and does not receive any funding from the sales of its products.
Interesting Cort. I am taking a product called CBDa by Planetaire. They went out of business and were bought by Tanasi who sell a combo of CBDa and regular CBD, saying studies show it works better than either alone. I’ll try these you mention next although can’t say I’ve noticed a difference with any of them. Thought about trying psilocybin but since I can’t handle THC a doc thought it might be problematic too. More importantly, Happy Birthday! 🙂
Thanks for the birthday greetings! 🙂
You’re welcome Cort, and thanks so much for all the great info you bring us. Glad you’ve found some low cost things that are helping. I’ve started blood restriction training, not low cost as unit was 400.00, but broke femur and then had disastrous knee replacement, so when I heard Peter Attia say he doesn’t know why all older folks who are in bed a lot due to operations aren’t being put on it, thought I’d better do it as so little movement in past 3 years. Amazing that in a town of 700,000 very few in medical profession are very familiar with it if at all, that I can tell, and only 2 PT places have the 5700K machines. I hope the home unit price comes down as so many with chronic illness would likely benefit. Surprised it’s not better known/used in physical therapy.
Happy birthday! I hope you had a great day and have a fantastic year ahead. Thank you for helping all of us make our lives as best they can be!
I am very intrigued by the series of low cost- no cost approaches.
My only concern with this potential treatment is whether or not it will affect people who have mass cell activation syndrome, and may have an allergic reaction to these products. I guess it’s worth a try. The overall outcome of calming the nervous system would be phenomenal!
Thanks for the birthday greetings, Kathleen :). I too am really intrigued about the possibility of finding low-cost things that can help. Stopping wheat, stretching and to my really great surprise – exercise bands – have been low-cost things that have helped me recently.
Hi, Kathleen, I have MCAS and found that Cannanda’s CB2 actually helps, rather than than triggers, the histamine reaction. I’ve also noticed that it helps reduce the pain and fatigue I have related to Fibromyalgia and Chronic Fatigue Syndrome. Everyone’s different, of course, and your reaction may not be like mine, but it may be worth trying. If you decide to give it a try, I hope it helps you as much as it has helped me!
Hi Barbara, I’ve just got the cb2 wellness drops, but not sure how often to take. I’d be very interested to know what you have tried?
Hi, Ruth, My husband and I have been taking the Cannanda CB2 Hemp Seed Oil (Ginger Flavor). It also says, “Terpene-Infused Cold-Pressed Raw Hemp Seed Oil” on the label. The suggested use is 1 – 2 tablespoons daily with meals. It’s sweetened with monk fruit extract, so it’s quite sweet tasting. It also comes in an Orange Creamsicle flavor and plain. Cost is about $39+ a bottle, but less if you buy in sets of 3 or 6.
HI, Ruth, I’ve been using the CB2 Hemp Seed Oil in the ginger flavor.
Hi Barbara
I see you are taking a Cannada CB2 product and report that it has helped with your Fibromyalgia and consequential fatigue.
I just ordered the CB2 Wellness.
I am curious if you are using the CB2 Wellness or the CB2 Hemp oil? I was confused when I ordered the product. I just received mine Sat. Sept 23rd so I can’t give any feedback on whether it is helping yet.
Which product or products are you using and are you inhaling or ingesting? The CB2 wellness says you can do either. But I’m curious if one way is more effective than the other. One more question if you don’t mind. How long after taking it do you start getting relief?
I am so hoping this product helps me with my FM pain I have tried so many things without success. Seems nothing helps.
Hi, Margo! Happy to help if I can! I’m taking the CB2 Hemp Seed Oil (ingesting). I haven’t tried the inhaling version, so can’t comment. I started noticing a subtle improvement after taking it for about a week. Although it has helped with my FM/CFS pain and sleep issues, it’s not a dramatic, OMG! improvement. More subtle, but noticeable. I do a LOT of other things to help minimize my FM/CFS symptoms: Ari Whitten’s The Energy Blueprint Program, diet, lifestyle, infra-red sauna, Traditional Chinese Medicine, supplements, gentle exercise (Yoga, Tai Chi), stress management, etc. The list is long, and there isn’t any ONE thing that eliminates the pain and fatigue, but that’s what it takes for me to get through most days with minimal symptoms. I NEVER have a day without SOME pain and fatigue, and I still experience severe flare-ups, too. I wish I could be more encouraging, but FM and CFS are complicated and everyone’s body is different, so what works for me might not be as helpful for you, but I still think it’s worth a try. I hope the Cannanda works for you! Good luck! Barbara
Thank you Barbara.
I understand with FM/ CF it definitely is an individuals struggle with what helps or not.
FM is definitely a struggle to put it mildly. I’m not able to use the approved medications, too many side effects outweighed the benefits.
I will post to all my experience with Cannada’s CB2 Wellness.
I wasn’t able to tolerate any of the prescription medications various Western doctors have prescribed, so I understand! That’s why I turned to Traditional Chinese Medicine and it has helped. I take a blend of Chinese herbs prescribed by my TCM doc for FM that you may want to consider trying. I’ve found it provides better pain relief than any of the prescription drugs I’ve tried (but only in combination with all the other things I do to minimize symptoms). In case you’re interested, it’s called Sappan 12, is made by Seven Forests, and is available on Amazon for $33.99 for 100 tablets. Might be worth a try, who knows?! Good luck!
Thanks Barbara
I may just try it
You’re welcome!
I’ve been researching MCAS and other stuff and the vast majority of MCAS also have mold toxicity. I only mention this bec it opened my eyes to a path that may help me and if it cd be helpful to you, I’m mentioning it here also. One mold-distinctive symptom is an “internal tremor” so if you have that and MCAS I suggest maybe checking out mold specialists docs. The ones I study right now think that MCAS will stabilize/heal/disappear or diminish once the mold is dealt with. Hopeful!
It’s not clear at all from here OR their website WHICH product you’re recommending – is there a specific one? Thanks.
I’d like to see where they make the claim that it usually works quickly – that would be nice. So many things you have to take forever to get any help from.
The ones I’m most interested in are the CB2 Wellness and Immune high ground ones. The CB2 Wellness seems like its their biggest seller.
https://cannanda.com/en-us/collections/frontpage/products/cb2-wellness?variant=42634386112737
https://cannanda.com/en-us/collections/frontpage/products/high-ground-immune
I’m also – not surprisingly (lol) – interested in the one pinene terpene one that purportedly helps with focus. It does not impact the endocannabinoid system. It’s aromatic – you put some drops in your hands and inhale.
The CB2 Wellness can be inhaled or taken orally or used as an ointment. The High Ground is inhaled.
https://cannanda.com/en-us/collections/frontpage/products/high-ground-immune
Thanks – inhaling is one thing I won’t do, but I’ll look at the other things. Essential oils and odors drive me crazy – they never saturate, so I can’t get rid of the smell.
Everything I use has to be free of added ‘fragrances’ – I can’t understand how people would use Febreeze ever, and can’t be in a room with someone who has perfume or cologne on.
Most of these things add a strong odor on top of the smell – they don’t remove the smell, so then I have to cope with TWO irritating things. Pain in the neck, like most of the ME/CFS symptoms.
Hi Alicia, I sympathize; I have the same issues with many chemicals and fragrances, particularly articial fragrances. The one good thing about having the ultrasensitive nose that goes with this illness? I can tell real olive oil from adulterated just by the smell!
. I also have major skin reactions if I use anything artificial or chemical on my skin, or if I don’t rinse the laundry at least TWICE, etc. And light and noise sensitivity, too….
Febreze made me violently ill the one and only time I allowed it in my house. I also had to banish Pledge and other nasty cleaning products. Knowing that my dogs noses are 1000x more sensitive than my own, the only humane thing to do – for me and the dogs – is to eliminate those items completely.
That said, I can tolerate, or even enjoy, certain pure essential oils in tiny quantities (I sometimes add a drop or two to the wash cycle in place of chemical laundry fresheners).
And I’m okay with fragrances coming from natural, organic foods or teas with nothing chemical added. Spices and scented herbs, for example, are not typically a problem.
I am also confused as to which Cannanda product might be most appropriate for MECFS.
The ones I’m most interested in are the CB2 Wellness and Immune high ground ones. The CB2 Wellness seems like its their biggest seller.
https://cannanda.com/en-us/collections/frontpage/products/cb2-wellness?variant=42634386112737
https://cannanda.com/en-us/collections/frontpage/products/high-ground-immune
Happy birthday Cort.
I just ordered the CB2 wellness and a bottle of hemp seed oil. I’ll add CBD to the mix and let you all know how it works. Thanks for the recommendation
it would be great, at least for us post menopausal women with CFS, if it does increase bone density.
Are there American companies that offer this? I don’t want to pay $20 for shipping and handling from Canada as well as $20 to ship it back if it doesn’t work
Yes, have a look on the Cannada link in Cort’s post.
Thanks but I’m not sure if you understood my request. Cannada is located in Canada. I’m looking for a US based source
I did but didn’t explain well sorry! Click on the Cannada link and there are details about international stockists.
Interesting! I’ve ordered one of Cannanda’s products to try out. I looked at the website and saw that Lee Know ND is one of the co-founders, I read his book on mitochondria a while ago and trust his name. Also, their products are carried in a health store near me.
I thought people might be interested in this article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120914/
Funnily enough , I have cravings for many of these sources of terpenes . I do like to get help from foods and natural sources as much as possible , so will add more of these to my regimen .
Thanks as always , Cort , and Happy Birthday .
You can’t get even close to a medicinal amount of these terpenes by food sources alone.
Thanks , Kelly . That’s good to know .
Thought people might be interested in this article
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120914/
Thanks , Cort , & Happy Birthday !
Just a comment for people unfamiliar with cannabis, on the statement that, THC is for pain and CBD is for inflammation/ anxiety. Maybe that’s referring to CBD isolate but that has pain relieving properties as well. Full spectrum CBD (.03% THC) (FSCBD) is an excellent pain reliever for everyday/ordinary pain. Only for severe pain does added THC provide benefit. I had meningitis and it was only with that amount of pain that I was taking a higher dose of THC, and pain was manageable before any signs of impairment were noticed. If you buy a FSCBD from a reputable (3rd party certified!) company, in a tincture or oil form, you can titrate your dose by the drop depending on your pain level.
What’s this? It was Cort’s birthday? Plenty of hugs going your way. 🙂
This is extremely interesting.
I’m being prescribed CBD by a doctor at the Sante Cannabis clinic (Canada).
I take it orally in capsules of 20 mg, 2 / day. I find it pretty stimulant and it helps a lot with the ME. I sometimes indulge in gummies, as they tend to work faster.
My doctor insisted that I also take THC to deal with insomnia. I’m not so fond of THC. I’ve reduced my intake from the prescribed 20 mg at night to 2,5 mg. And even so, not every night. I found it might help me stay asleep, but not help me fall asleep.
The one thing I have found that works for pain and as an anti-inflammatory is a trans-dermal cream which contains an equal quantity of THC and CBD. The trans-dermal quality is very efficacious. It starts working in less than 5 minutes. I slab it on when I go to bed.
I don’t think I can import products from Green Light, but thank you Cort, for putting out this practical kind of information.
Even though in Quebec, where I live, one can buy cannabis related products in government managed stores, I prefer ordering on-line from a Canadian supplier (Spectrum Therapeutics) which is well respected, has labs where qualified staff meticulously isolate the different components of cannabis. The dosage of THC, CBD, CBN, CBG… is calibrated with precision and I trust that what’s indicated on the package is accurate, including the type of plant from which these components have been isolated.
When I first started the therapy, about 9 months ago, I had a lot of questions and there was always someone knowledgeable to whom to talk. They’re expensive, though.
Now, I will certainly research beta-caryophyllene and see if I can integrate it in my “protocol”.
Cheers!
It is hard to work out from the news media what the real chances are of the DEA reclassifying marijuana as a class III (and open the door to medical research in the US):
https://www.wdrb.com/news/politics/move-to-reclassify-marijuana-on-federal-level-gives-hope-to-kentucky-weed-advocates/article_3818e224-4901-11ee-b968-e312b33d60aa.html
Is there a specific product sold by those two companies which you would recommend for a patient with ME/CFS & LongCovid?
Copaiba is an essential oil and not so much a company. If you go to Florihana’s website they will actually list the % of beta-caryophyllene and their latest batch had 46% in it, it seems.
There was one report on PR that claimed huge success vaporizing/inhaling the essential oil.
https://forums.phoenixrising.me/threads/curcumin-caryophyllene-and-the-cannabinoid-connection.87184/
Beta-caryophyllene is also one of the ingredients of Inspiritol.
I was researching both products and read that copaiba has naturally occurring compounds that are hepatotoxic, whereas Cannanda’s CB2 claims to only use “GRAS status” ingredients. I quote Cannanda “100% GRAS status (Generally Recognized As Safe), making CB2 as safe to consume as food.” Based on this alone, I feel CB2 might be the better option for me personally. I’ll give the CB2 oil a try and see how it goes!
Are these available in UK please?
Yes they are. Go to Corts link to Canada then find where UK stockists are. I’ve just got mine. 😊
Cannanda’s UK distributor (from their website): https://www.greenterpenes.co.uk/shop/
Thanks Cort, I’ve just received cb2 wellness and am going to give it a go for ME, alongside my CBD, which is not so effective. Thank you and happy birthday 🎉.
Thanks! Good luck!
Thanks! Instant pain relief effect and sinus unblocking.
‘ A black pepper extract called Viphyllin™ containing 30% β-caryophyllene reduced anxiety-like behavior, brain antioxidant status, intestinal inflammation, and intestinal barrier function in an animal model.’
I cannot find anything about this in the article it links to.
I find the ingredients quite vague: ‘food-grade terpenes extracted from botanical essential oils)’. No list of the specific terpenes and the amount of them in each dose.
Happy belated birthday Cort.
AND A BIG THANK YOU FOR ALL YOU ARE DOING!!!9
Hi, I just got a bottle of CB2 Wellness. But I haven’t seen any dosing instructions – how much is recommended? and how? and when (with/without food/drink etc) ?
PS – (forgot to add) the instructions on the website are various avenues (inhaling, rubbing, under tongue) but no info as to which method is best for what….
I just received my CB2 Wellness.
It is 2 to 3 drops either rubbed in hands cupping hands around nose and inhaled for 1 to 2 minutes OR 2to 3 drops under the tongue. Let sit for a minute or 2 then swallow.
I hope it works
I’m so tired of living with daily chronic pain of FM. Hope it works for you too.
Hey Cort, have you seen the results about Dr Jared Younger GWI trial about the natural supplements? Out of the 12 tested (line St John’s Wort), the only molecule working seems to be Curcuma with Peperine included. Dr Younger was guessing that the results would likely be the same with ME/CFS and FM.
I have chronic fatigue syndrome of eight months duration, and since I started taking the CB2 hemp seed oil three weeks ago, I’m feeling SO MUCH BETTER. It helps me in four ways that I can detect:
• Improved my sleep – I felt the effect on the first night! Taking two caps after dinner each night helps me stay asleep instead of waking at 3 am.
• Gave me more energy – I have gone from having to lie down most of the day, to now being up and around all day! I can go out and meet up with friends, do errands, even do yard work! I’ve doubled my daily steps from 3500 to more than 7000.
• Eliminated exertion intolerance – When I do more physical activity than I’m used to, instead of feeling sick and brain-fogged the next day, I just feel tired. I feel almost normal again!
• Reduced inflammation – I broke my wrist 8 months ago, and in the past 3 weeks, there has been a big drop in the inflammation, pain, and tingling in my hand. I can now use my hand almost completely normally!
The results have been so dramatic! Wish I could have accessed CB2 a long time ago, because then I wouldn’t have had to experience so many years of physical disability and missing out on life. I started to feel more “normal” in just one week. Knowing the normal progression of recovery for chronic fatigue syndrome, I can’t believe how much healthier, stronger, more whole, and “normalized” I felt in just three weeks!
Nice! Thanks for sharing. 🙂
I wonder if this is the answer as many with CFS and Fibromyalgia have mast cell activation..or at least suspected to have it. Epicutaneous Sensitization to the Phytocannabinoid β-Caryophyllene Induces Pruritic Inflammation
Thanks, Cort.
I’m a fifty-year+ fibromyalgia sufferer and follow your blog religiously. I’m also likely to give every supposed or proposed solution that I can afford a chance. For the past month, I’ve included terpenes in my fibromyalgia regimen. I’ve tried Cannanda’s CB2 Salve, CB2 Oil, and Wellness Blend with positive results. The salve has worked to provide me with pain relief when applied topically to various body parts. I believe the CB2 oil has helped to reduce inflammation in my hands, feet, and elbows. I also use Cannanda’s Wellness Blend as part of my daily terpenes routine. I can certainly recommend these products after my short-term trial.
I also strongly recommend becoming a sustaining contributor to Health Rising.
Keep up the good work
Great to hear things are working David (and thanks for the plug!) 🙂
I don’t know where I would be without cannabis for sleep, I really don’t. Plus when I take it when I wake up at night it leaves me relaxed and more able to go on a walk in the morning. It is really hitting some hot spots.