Wound up, Overheated and Tweaked: A Look at the Fibromyalgia Brain and Nervous System.
In “Key Milestones Contributing to the Understanding of the Mechanisms Underlying Fibromyalgia”, two Australian researchers give a fascinating overview of what they consider to be the breakthrough findings in FM. Tellingly, they quickly highlight...
Surprise Gene Finding Could Give Pathogens and Toxins a Leg Up in ME/CFS
Travis Craddock heads Dr. Klimas’s biocomputational modeling team at the Institute for Neuroimmune Medicine (INIM) at Nova Southeastern University. This is the team responsible for crunching the hundreds of thousands of data points gathered from Dr....
Could Neuroinflammation Be Triggering the Cortisol Issues in ME/CFS and Fibromyalgia?
“Therefore, in this study, we hypothesize that understanding cortisol patterns in both these syndromes may be a crucial factor in characterizing FMS and CFS.” The authors More than any other substance, cortisol demonstrates how integral a role the stress...
From Fight/Flight to Neuroinflammation: Explaining the “Functional Pain” in Fibromyalgia and ME/CFS?
Sustained Stimulation of β2- and β3-adrenergic Receptors Leads to Persistent Functional Pain and Neuroinflammation. Xin Zhang, MD, PhD, Jane E. Hartung PhD, […], and Andrea G. Nackley PhD, PhD. Brain Behav Immun 2018 Oct;73:520-532. doi:...
A Novel Neuroinflammatory Paradigm for Chronic Fatigue Syndrome (ME/CFS)
Two New Zealanders combine neuroinflammation with the HPA axis to produce a unique explanation for ME/CFS and FM. Neuroinflammation, the hypothalamus and a unifying hypothesis Mackay A, Tate WP. A compromised paraventricular nucleus with a dysfunctional hypothalamus:...Lives Interrupted Latest Story
Bob Graybosch
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