One of the dangers facing the long-COVID research field was an over-emphasis on immune functioning and an under-emphasis on metabolism and energy production. While exercise studies showed up pretty early in chronic fatigue syndrome (ME/CFS), it took the field a while...
Clinical trials – once a rarity for chronic fatigue syndrome (ME/CFS) – suddenly seem to be popping up all around the place. The Open Medicine Foundation just announced its first two-fer (two drugs tested together) clinical trial, Solve M.E. has funded at...
We continue to take a deep dive into the “Long COVID and Post Acute Sequalae of SARS CoV 2 (PASC): Pathogenesis and Treatment” first-ever international conference on long COVID. Long-COVID research was always going to be a bit messy. Take a look at the...
The “WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome” study is fraught with possibility. For one, it was published in The Proceedings of the National Academy of Sciences...
Ischemia–reperfusion injury, hypoxia–reperfusion injury, or reoxygenation injury – whatever name you wish to call it – occurs when a low oxygen state in the tissues is followed by a resumption of normal oxygen flows. Oddly enough, it’s during the...
The title of this metabolomic study “Evidence for Peroxisomal Dysfunction and Dysregulation of the CDP-Choline Pathway in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome” made it clear that something new was in the works. Peroxisomal dysfunction had...
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