Fibromyalgia, chronic fatigue syndrome and other functional pain disorders may triggered by an overactive fight/flight system which results in neuroinflammation.
Intranasal preparations could speed the delivery of drugs and supplements like glutathione and insulin to the brain in chronic fatigue syndrome and fibromyalgia and reduced inflammation there.
The authors propose that a new approach to fibromyalgia is needed to produce better drug treatments. They focused on cannabinoids, NMDA receptors, neuroinflammatory drugs, etc.
Two ME/CFS, yes, ME/CFS low dose naltrexone papers appear, one fibromyalgia report attempts to turn dosing protocols on their head, one patient blows through normal dose levels with spectacular success, Jarred Younger hunts for a more powerful naltrexone, and then...
Did the FDA mess up the biggest fibromyalgia drug trial ever? The trial authors propose that changes the FDA made doomed the putative replacement for Lyrica called mirogabalin - and could impair future drugs from becoming approved.
It was a project birthed in hope. Pal Schaathun, a Norwegian filmmaker would document what he hoped might be the end of chronic fatigue syndrome (ME/CFS). That, unfortunately, turned out not to be but Schaathun ended up documenting – in strikingly beautiful...
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