“You really need the THC in there to get the medicinal benefits of the cannabis,” Marcu said. “CBD has not been found to be very effective by itself. [Using a 1:1 ratio] will probably give you the best chance for a positive therapeutic improvement.”
Dr. Michelle Sexton, a naturopathic doctor, uses CBD oil as a treatment in her San Diego practice. She usually starts patients at an extremely high CBD to THC ratio (18:1) and then increases the THC content as needed for symptom relief.
“Everyone has to find their comfort zone,” said Martin Lee, founder of Project CBD, a California-based nonprofit dedicated to promoting and publicizing research into the medical uses of CBD and other components of the cannabis plant.
Like every medical treatment, some patients with chronic pain respond well to CBD-rich products and others do not.
“I think it depends on the types of pain you have,” Sexton said. “Any type of pain that seems to neuropathic seems to respond.”
Anecdotally, the best ways to use CBD-rich products seem to be sublingually (placing drops of the oil under the tongue) or through inhalation (vaping is preferable to smoking). But there are topical and edible products available as well.
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For those who live in states where marijuana is legal, almost any dispensary carries CBD-rich products these days. The package should indicate the ratio of CBD to THC to make selection easier.